NOW Foods P-5-P

Name: NOW Foods P-5-P
Brand: NOW Foods
SKU: 733739004611
Price: 12.99 GBP
Availability: InStock

Brands: NOW Foods

£12.99

Vitamin B6, delivered in NOW Foods' vcaps format.

Why people take it

Vitamin B6 contributes to normal protein and glycogen metabolism
Vitamin B6 contributes to the regulation of hormonal activity
Vitamin B6 contributes to the reduction of tiredness and fatigue

How to use

Take as directed on the pack, ideally with food and at the same time each day.

Good to know

Format: vcaps
Caffeine free
Vegetarian-friendly capsule shell

A food supplement, not a substitute for a varied diet and healthy lifestyle. Do not exceed the stated dose. Keep out of reach of children.

Quantity

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Categories : Caffeine-Free Supplements, Everyday Health Supplements, NOW Foods, Vegetarian Supplements, Vitamin B12 & B Complex, Vitamins & Supplements

SKU: 733739004611

At a glance

£0.14

per daily dose

Limited

evidence for vitamin b6

Our honest take

P-5-P (pyridoxal-5-phosphate) is the active form of vitamin B6: each capsule gives 50 mg of P-5-P, equal to 33 mg of vitamin B6, plus 25 mg of magnesium. That is more than three times the FSA's advice of no more than 10 mg of B6 a day from supplements long term, and high doses can damage nerves. There is little evidence that P-5-P does anything better than ordinary pyridoxine for most people, and adults need only about 1.4 mg of B6 a day.

A doctor has advised you to take the active form of B6 at a set dose
You have not been advised to take B6: most people get enough from food
You already take a B complex, multivitamin or magnesium/zinc product with B6
You have tingling, numbness or burning in your hands or feet, or take levodopa, phenytoin or phenobarbital

The science

Vitamin B6· evidence: Limited

Vitamin B6 (pyridoxine, or the active form pyridoxal-5-phosphate, P-5-P) helps the body use protein and make red blood cells and some brain chemicals. Adults need only about 1.2 to 1.4 mg a day, and most people in the UK get this easily from meat, fish, wholegrains, potatoes, bananas and fortified cereals. True deficiency is uncommon.

For people who are not deficient, there is little good evidence that extra B6 does anything useful. It is often combined with magnesium or zinc in sports products; the B6 in these is mostly there to carry the label claims.

The bigger issue with B6 is safety. Long-term high doses can damage the nerves in the hands and feet, and this has been reported at doses sold freely in shops.

Authorised health claim
Vitamin B6 contributes to normal cysteine synthesis. Vitamin B6 contributes to normal energy-yielding metabolism. Vitamin B6 contributes to normal functioning of the nervous system. Vitamin B6 contributes to normal homocysteine metabolism. Vitamin B6 contributes to normal protein and glycogen metabolism. Vitamin B6 contributes to normal psychological function. Vitamin B6 contributes to normal red blood cell formation. Vitamin B6 contributes to the normal function of the immune system. Vitamin B6 contributes to the reduction of tiredness and fatigue. Vitamin B6 contributes to the regulation of hormonal activity. (Applies where a daily dose gives at least 15% of the NRV, i.e. 0.21 mg.)

Typical dose: Adults need about 1.2 mg (women) to 1.4 mg (men) a day (NRV on labels: 1.4 mg). A supplement giving 1.4 to 10 mg is plenty.

Safety: The Food Standards Agency advises not taking more than 10 mg of vitamin B6 a day from supplements unless a doctor advises it. Taking more than this for a long time can cause loss of feeling in the arms and legs (peripheral neuropathy). Add up the B6 from all your supplements, including B complexes, magnesium/zinc products and multivitamins. Stop and see your GP if you notice tingling, numbness or burning in your hands or feet.

Research we looked at:
NHS. Vitamins and minerals: vitamin B6. nhs.uk/conditions/vitamins-and-minerals/vitamin-b
Expert Group on Vitamins and Minerals (2003). Safe Upper Levels for Vitamins and Minerals. Food Standards Agency.
EFSA NDA Panel. Scientific opinion on the tolerable upper intake level for vitamin B6. EFSA Journal 2023;21(5):8006.
Therapeutic Goods Administration (Australia) 2023. Safety review: vitamin B6 (pyridoxine) and peripheral neuropathy.

Ingredients & nutrition

Per daily dose (1 capsule): vitamin B6 33 mg (2,357% NRV) from 50 mg pyridoxal-5-phosphate monohydrate; magnesium (bisglycinate) 25 mg (7% NRV). 90 capsules, 90 daily doses.

Other ingredients: rice flour, hypromellose (cellulose capsule), microcrystalline cellulose, stearic acid, silicon dioxide. Suitable for vegetarians and vegans.

Always check the pack you receive, as manufacturers sometimes update recipes.

How to use

Label directions: 1 capsule a day with a meal, adults only. Do not exceed the stated daily dose. Do not take long term without medical advice, and stop if you notice tingling or numbness in your hands or feet.

Price per dose & how it compares

Product	Size	Price	Per daily dose
This product	90 vcaps	£12.99	£0.14
Osavi Vitamin B6 Pyridoxal-5-Phosphate		from £6.19	£0.10
Cytoplan Vitamin B6		from £13.99	£0.42
Life Extension Vitamin B6		from £9.99	–

Cost per daily dose lets you compare packs of different sizes fairly.Worked out from our current prices.

Food supplements should not replace a varied, balanced diet and healthy lifestyle. General information, not medical advice. Speak to your GP or pharmacist first if you are pregnant or breastfeeding, have a medical condition or take medication.