Life Extension Vitamins D and K with Sea-Iodine

Name: Life Extension Vitamins D and K with Sea-Iodine
Brand: Life Extension
SKU: 737870204060
Price: 22.25 GBP
Availability: InStock

Brands: Life Extension

£22.25

Vitamin D, vitamin K and iodine together, delivered in Life Extension's caps format.

Why people take it

Vitamin D contributes to the normal function of the immune system
Vitamin D contributes to the maintenance of normal bones and teeth
Vitamin D contributes to normal absorption and utilisation of calcium and phosphorus
Vitamin K contributes to the maintenance of normal bones
Vitamin K contributes to normal blood clotting
Iodine contributes to normal thyroid function
Iodine contributes to normal cognitive function

How to use

Take as directed on the pack, ideally with food and at the same time each day.

Good to know

Format: caps
Caffeine free

A food supplement, not a substitute for a varied diet and healthy lifestyle. Do not exceed the stated dose. Keep out of reach of children.

Quantity

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Categories : Caffeine-Free Supplements, Everyday Health Supplements, Life Extension, Vitamin D Supplements, Vitamins & Supplements

SKU: 737870204060

At a glance

£0.37

per daily dose

Strong

evidence for vitamin d3

Our honest take

A high-dose combination: each capsule gives 125 µg (5,000 IU) of vitamin D3, 2,100 µg of vitamin K (K1, MK-4 and MK-7) and 1,000 µg of iodine. The vitamin D and iodine are both above the levels UK and EU experts set as safe for long-term daily use (100 µg and 600 µg), and the vitamin K is around 28 times the daily reference intake. Most people need only 10 µg of vitamin D in autumn and winter, so we would not suggest this without medical advice.

You have been told by a doctor to take high-dose vitamin D with vitamin K, and are being monitored
You take warfarin or another blood thinner: vitamin K directly affects how it works
You have a thyroid condition or take thyroid medicines: the iodine dose is high
You just want everyday vitamin D: a 10 to 25 µg D3 is safer and cheaper

The science

Vitamin D3· evidence: Strong

Vitamin D3 (cholecalciferol) is the form the skin makes from sunlight. In the UK there is not enough strong sunlight from about October to March, so many people have low levels over winter. Good-quality trials show supplements reliably raise blood levels and correct deficiency, and that matters for bone health in people who are low.

The NHS advises everyone to consider 10 µg (400 IU) a day in autumn and winter, and all year round for people who get little sun, cover their skin, have darker skin or live in care homes. For people who already have adequate levels, large trials have not shown that extra vitamin D prevents falls, fractures or other illness.

In short: a modest daily dose is sensible and cheap insurance for most UK adults in winter. Very high doses are not better and should only be taken on medical advice.

Authorised health claim
Vitamin D contributes to the normal function of the immune system. Vitamin D contributes to the maintenance of normal bones. Vitamin D contributes to the maintenance of normal muscle function. Vitamin D contributes to the maintenance of normal teeth. Vitamin D contributes to normal absorption/utilisation of calcium and phosphorus. (Applies where a daily dose gives at least 15% of the NRV, i.e. 0.75 µg.)

Typical dose: 10 µg (400 IU) a day is the NHS advice for adults and children over 1. Doses of 25 µg (1,000 IU) to 50 µg (2,000 IU) are common and safe for adults. Babies under 1 need 8.5 to 10 µg a day unless they have more than 500 ml of formula.

Safety: Do not take more than 100 µg (4,000 IU) a day without medical advice (FSA/NHS); children aged 1 to 10 should not have more than 50 µg, and babies under 1 no more than 25 µg. Long-term very high intake can raise blood calcium, which can damage the kidneys and heart. People with kidney disease, sarcoidosis or high calcium levels should speak to their GP first.

Research we looked at:
NHS. Vitamin D. nhs.uk/conditions/vitamins-and-minerals/vitamin-d
Scientific Advisory Committee on Nutrition (SACN). Vitamin D and Health. 2016.
EFSA NDA Panel. Scientific opinion on the tolerable upper intake level for vitamin D. EFSA Journal 2023;21(8):8145.
Bolland MJ, Grey A, Avenell A. Effects of vitamin D supplementation on musculoskeletal health: a systematic review, meta-analysis, and trial sequential analysis. Lancet Diabetes Endocrinol 2018;6(11):847-858.

Vitamin K2 (MK-7)· evidence: Limited

Vitamin K2 (menaquinone, usually as MK-7 in supplements) is one of the forms of vitamin K. The body needs vitamin K to make proteins involved in blood clotting and bone. Most adults get enough vitamin K from green vegetables, vegetable oils and some fermented foods, and true deficiency is rare in healthy adults.

Vitamin K2 is often sold alongside vitamin D3 on the idea that it helps direct calcium into bone. Trials of K2 on bone density and fractures are small and mixed, and the effect in well-nourished people is uncertain. Claims about arteries or heart health are not established.

Adding K2 to a vitamin D supplement is reasonable but not necessary for most people. It mainly adds cost.

Authorised health claim
Vitamin K contributes to normal blood clotting. Vitamin K contributes to the maintenance of normal bones. (Applies where a daily dose gives at least 15% of the NRV, i.e. 11.25 µg.)

Typical dose: Adults need about 1 µg per kg of body weight a day (around 70 µg for a 70 kg adult), mostly met by diet. Supplements usually give 45 to 200 µg of MK-7.

Safety: Vitamin K can stop warfarin and similar anticoagulants (vitamin K antagonists) working properly. Anyone on warfarin must not take vitamin K supplements without talking to their GP or anticoagulant clinic. The FSA notes that 1 mg or less a day from supplements is unlikely to cause harm in other people.

Research we looked at:
NHS. Vitamin K. nhs.uk/conditions/vitamins-and-minerals/vitamin-k
EFSA NDA Panel. Dietary reference values for vitamin K. EFSA Journal 2017;15(5):4780.
Mott A, Bradley T, Wright K, et al. Effect of vitamin K on bone mineral density and fractures in adults: an updated systematic review and meta-analysis of randomised controlled trials. Osteoporos Int 2019;30(8):1543-1559.

Iodine· evidence: Moderate

Iodine is needed to make thyroid hormones. Adults need about 140 µg a day in the UK, mainly from milk, dairy, eggs and white fish. Salt in the UK is rarely iodised, so people who avoid dairy and fish, including many vegans, can fall short. Getting enough matters most before and during pregnancy and breastfeeding.

A modest supplement (around 100 to 150 µg) is a sensible way to cover intake for people with low-iodine diets. There is no benefit to taking large amounts, and both too little and too much can upset thyroid function.

Seaweed and kelp products vary widely in iodine content, and some give far more than is needed.

Authorised health claim
Iodine contributes to the normal production of thyroid hormones and normal thyroid function. Iodine contributes to normal cognitive function. Iodine contributes to normal energy-yielding metabolism. Iodine contributes to the maintenance of normal skin. (Applies where a daily dose gives at least 15% of the NRV, i.e. 22.5 µg.)

Typical dose: Adults need about 140 µg a day from all sources (NRV on labels: 150 µg). Supplements usually give 75 to 150 µg.

Safety: The NHS advises that 0.5 mg (500 µg) a day or less from supplements is unlikely to cause harm; EFSA's adult upper level from all sources is 600 µg a day. Higher intakes can disturb thyroid function. Anyone with a thyroid condition, or taking thyroid medicine, should speak to their GP before taking iodine.

Research we looked at:
NHS. Others: vitamins and minerals (iodine). nhs.uk/conditions/vitamins-and-minerals/others
British Dietetic Association. Iodine: food fact sheet. bda.uk.com
EFSA NDA Panel. Scientific opinion on dietary reference values for iodine. EFSA Journal 2014;12(5):3660.

Ingredients & nutrition

Per daily dose (1 capsule): vitamin D3 (cholecalciferol) 125 µg / 5,000 IU (2,500% NRV); vitamin K 2,100 µg (2,800% NRV) as K1 (phytonadione) 1,000 µg, K2 MK-4 1,000 µg and K2 MK-7 100 µg; iodine 1,000 µg (667% NRV) from Sea-Iodine complex (organic kelp and bladderwrack extracts, potassium iodide). 60 capsules, 60 daily doses.

Other ingredients: microcrystalline cellulose, vegetable cellulose (capsule), maltodextrin, modified food starch, dicalcium phosphate, stearic acid, silica.

Always check the pack you receive, as manufacturers sometimes update recipes.

How to use

Label directions: 1 capsule a day with food. Do not exceed the stated daily dose. Only take on medical advice: the vitamin D and iodine are above UK guidance levels for long-term use. Do not take with warfarin or other blood thinners unless your doctor agrees.

Price per dose & how it compares

Product	Size	Price	Per daily dose
This product	60 caps	£22.25	£0.37
Apollo's Hegemony Vitamin D3 with K2 MK7		from £21.69	–
Aventus Supplements Vitamin D3 + K2		from £23.32	–
Allnutrition Vit D3 4000 + K2 Drops		from £8.39	£0.02

Cost per daily dose lets you compare packs of different sizes fairly.Worked out from our current prices.

Food supplements should not replace a varied, balanced diet and healthy lifestyle. General information, not medical advice. Speak to your GP or pharmacist first if you are pregnant or breastfeeding, have a medical condition or take medication.