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Life Extension Super Selenium Complex & Vitamin E
Life Extension Super Selenium Complex & Vitamin E gives you vitamin E and selenium in a vcaps format you can take with your first meal of the day.
Why people take it
- Vitamin E contributes to the protection of cells from oxidative stress
- Selenium contributes to the normal function of the immune system
- Selenium contributes to the maintenance of normal hair and nails
How to use
Take as directed on the pack, ideally with food and at the same time each day.
Good to know
- Format: vcaps
- Caffeine free
- Vegetarian-friendly capsule shell
A food supplement, not a substitute for a varied diet and healthy lifestyle. Do not exceed the stated dose. Keep out of reach of children.
At a glance
£0.10
per daily dose
Limited
evidence for selenium
Our honest take
A selenium capsule giving 200 µg of selenium from three forms (selenomethionine, sodium selenite and Se-methyl selenocysteine) plus 20 mg of vitamin E. 200 µg is nearly four times the daily reference intake: within UK safe limits on its own, but easy to overdo if you also take a multivitamin or eat Brazil nuts. There is no good evidence that mixing selenium forms helps people who are not deficient, and we make no claims about cancer or disease. At about 10p a day it is cheap.
- You eat little fish, eggs, meat or nuts and want a selenium top-up
- You want selenium and vitamin E in one capsule
- You already take a multivitamin with selenium or eat Brazil nuts regularly
- You eat a varied diet: most people get enough selenium from food
- You have a thyroid condition, without your doctor's advice
The science
Selenium· evidence: Limited
Selenium is a trace mineral needed for antioxidant enzymes, the immune system and thyroid hormone metabolism. Adults need 60 to 75 µg a day in the UK, from Brazil nuts, fish, meat, eggs and bread. UK intakes are on the low side of recommendations for some people, but clear deficiency is uncommon.
Large trials giving selenium to people who were not deficient (such as SELECT) found no protection against cancer or heart disease, and some hint of a higher risk of type 2 diabetes at higher intakes. Benefits are mainly expected in people who are actually low.
The range between enough and too much is narrow, so it is worth checking total intake from all supplements.
Selenium contributes to the normal function of the immune system. Selenium contributes to normal thyroid function. Selenium contributes to the protection of cells from oxidative stress. Selenium contributes to the maintenance of normal hair. Selenium contributes to the maintenance of normal nails. (Applies where a daily dose gives at least 15% of the NRV, i.e. 8.25 µg.)
Typical dose: Adults need about 60 µg (women) to 75 µg (men) a day from all sources (NRV on labels: 55 µg). Supplements usually give 50 to 200 µg.
Safety: The NHS advises that 350 µg a day or less from supplements is unlikely to cause harm; EFSA set a lower adult upper level of 255 µg a day from all sources in 2023. Too much over time can cause hair and nail loss, skin rashes and a garlic smell on the breath. Brazil nuts are very high in selenium, so count them if you also take a supplement.
Research we looked at:
NHS. Others: vitamins and minerals (selenium). nhs.uk/conditions/vitamins-and-minerals/others
EFSA NDA Panel. Scientific opinion on the tolerable upper intake level for selenium. EFSA Journal 2023;21(1):7704.
Rayman MP. Selenium and human health. Lancet 2012;379(9822):1256-1268.
Vitamin E· evidence: Limited
Vitamin E is a group of fat-soluble compounds (tocopherols and tocotrienols); alpha-tocopherol is the form the body keeps and the one labels count. It is found in plant oils, nuts and seeds, and the NHS says you should be able to get all you need from your diet. Deficiency is very rare and usually linked to conditions that stop fat being absorbed.
Large, long trials of high-dose vitamin E have not shown benefits for heart disease, cancer or general health in well-nourished people. Some found possible harm: the SELECT trial found more prostate cancer in men taking 400 IU a day, and a meta-analysis linked very high doses to slightly higher overall mortality.
Natural vitamin E (d-alpha-tocopherol) is more potent per IU-labelled milligram than synthetic (dl-alpha). Mixed tocopherols and tocotrienols are marketed as closer to food, but there is little good human evidence that they make a difference.
Vitamin E contributes to the protection of cells from oxidative stress. (Applies where a daily dose gives at least 15% of the NRV, i.e. 1.8 mg.)
Typical dose: UK guidance: about 4 mg a day for men and 3 mg for women (NRV on labels: 12 mg). Supplements often give 100 to 400 IU (roughly 67 to 268 mg natural vitamin E).
Safety: The FSA advises that 540 mg (800 IU) a day or less from supplements is unlikely to cause harm; EFSA's upper level for adults is 300 mg a day. High doses can increase bleeding risk, so speak to your GP if you take warfarin, other anticoagulants or antiplatelet drugs, or before surgery. Long-term high-dose use is not advised for smokers or men concerned about prostate health.
Research we looked at:
NHS. Vitamin E. nhs.uk/conditions/vitamins-and-minerals/vitamin-e
EFSA NDA Panel. Scientific opinion on dietary reference values for vitamin E as alpha-tocopherol. EFSA Journal 2015;13(7):4149.
Klein EA, Thompson IM, Tangen CM, et al. Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA 2011;306(14):1549-1556.
Miller ER, Pastor-Barriuso R, Dalal D, et al. Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality. Ann Intern Med 2005;142(1):37-46.
Ingredients & nutrition
Always check the pack you receive, as manufacturers sometimes update recipes.
How to use
Price per dose & how it compares
| Product | Size | Price | Per daily dose |
|---|---|---|---|
| This product | 100 vcaps | £10.49 | £0.10 |
| NOW Foods Selenium | from £4.99 | £0.05 | |
| Life Extension Se-Methyl L-Selenocysteine | from £11.93 | £0.13 | |
| Osavi Selenium | from £6.85 | £0.08 |
Cost per daily dose lets you compare packs of different sizes fairly.Worked out from our current prices.
Food supplements should not replace a varied, balanced diet and healthy lifestyle. General information, not medical advice. Speak to your GP or pharmacist first if you are pregnant or breastfeeding, have a medical condition or take medication.
Life Extension Super Selenium Complex & Vitamin E gives you vitamin E and selenium in a vcaps format you can take with your first meal of the day.
Why people take it
- Vitamin E contributes to the protection of cells from oxidative stress
- Selenium contributes to the normal function of the immune system
- Selenium contributes to the maintenance of normal hair and nails
How to use
Take as directed on the pack, ideally with food and at the same time each day.
Good to know
- Format: vcaps
- Caffeine free
- Vegetarian-friendly capsule shell
A food supplement, not a substitute for a varied diet and healthy lifestyle. Do not exceed the stated dose. Keep out of reach of children.
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