Size
Doctor's Best Glucosamine
Doctor's Best Glucosamine keeps it simple: glucosamine, 1500mg across 180 caps.
What it is
- Glucosamine, a building block of cartilage, taken from shellfish or fermented corn
- Commonly combined with chondroitin and MSM in joint formulas
How to use
Take as directed on the pack. Joint formulas are normally taken daily over a longer run rather than as a one-off.
Contains shellfish-derived glucosamine unless the pack states otherwise — check before use if you have a shellfish allergy.
Good to know
- Format: caps
- Caffeine free
A food supplement, not a substitute for a varied diet and healthy lifestyle. Do not exceed the stated dose. Keep out of reach of children.
At a glance
£0.19
per daily dose
Limited
evidence for glucosamine
Our honest take
The best-value way we sell to try glucosamine on its own: two capsules give 1,500 mg of glucosamine sulphate, the dose used in research, for about 20p a day. There is nothing else in it, which we see as a plus. The honest catch is that large independent trials found little benefit over a dummy pill for most people and there is no authorised health claim, so give it around three months and stop if you notice no difference.
- You want to try glucosamine at the studied dose for the lowest cost
- You do not want chondroitin or other extras
- You are allergic to shellfish (glucosamine from crab and shrimp shells)
- You take medicine for diabetes, glaucoma or blood thinning, or are pregnant: check with your doctor first
- You are vegetarian (gelatin capsules): NOW or Doctor's Best vegan glucosamine suit you better
The science
Glucosamine· evidence: Limited
Glucosamine is a building block of cartilage. In supplements it comes as glucosamine sulphate or glucosamine hydrochloride, usually made from crab and shrimp shells, or from fermented corn in vegan versions. N-acetyl glucosamine is a related form with even less research behind it.
It has been studied a lot, and the results are disappointing. Large independent trials, such as the US GAIT trial, and a big review of the research found little or no difference from a dummy pill for most people. Some earlier trials using one branded glucosamine sulphate looked better, but many of those were funded by the maker. NICE does not recommend glucosamine on the NHS, and EFSA rejected a claim that it helps keep joints healthy.
There is no authorised health claim for glucosamine, so we make no claims about what it does. If you want to try it, the dose used in studies is 1,500 mg of glucosamine sulphate a day, and it is fair to stop after about three months if you notice no difference.
Typical dose: Studies used 1,500 mg of glucosamine sulphate a day
Safety: Most glucosamine is made from shellfish: avoid unless the label says it is from a non-shellfish source if you have a shellfish allergy. Glucosamine may strengthen the effect of warfarin, so speak to your GP or pharmacist first if you take warfarin or another blood thinner. Speak to your GP first if you have diabetes, asthma or glaucoma, or are pregnant or breastfeeding. Can cause mild stomach upset.
Research we looked at:
Clegg DO et al. (2006). Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. N Engl J Med 354:795–808.
Wandel S et al. (2010). Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of hip or knee: network meta-analysis. BMJ 341:c4675.
NICE (2022). Osteoarthritis in over 16s: diagnosis and management. NICE guideline NG226.
EFSA NDA Panel (2009). Scientific opinion on the substantiation of health claims related to glucosamine alone or in combination with chondroitin sulphate and maintenance of joints. EFSA Journal 7(9):1264.
Ingredients & nutrition
Always check the pack you receive, as manufacturers sometimes update recipes.
How to use
Price per dose & how it compares
| Product | Size | Price | Per daily dose |
|---|---|---|---|
| This product | 1500mg - 180 caps | £17.99 | £0.19 |
| NOW Foods Glucosamine 1000 | from £22.99 | £0.26 | |
| NOW Foods Glucosamine & Chondroitin Extra Strength | from £19.99 | £0.62 | |
| Doctor's Best Vegan Glucosamine with GreenGrown | from £20.99 | £0.23 | |
| Doctor's Best Glucosamine Chondroitin MSM with OptiMSM | from £57.99 | £0.64 |
Cost per daily dose lets you compare packs of different sizes fairly.Worked out from our current prices.
Food supplements should not replace a varied, balanced diet and healthy lifestyle. General information, not medical advice. Speak to your GP or pharmacist first if you are pregnant or breastfeeding, have a medical condition or take medication.
Doctor's Best Glucosamine keeps it simple: glucosamine, 1500mg across 180 caps.
What it is
- Glucosamine, a building block of cartilage, taken from shellfish or fermented corn
- Commonly combined with chondroitin and MSM in joint formulas
How to use
Take as directed on the pack. Joint formulas are normally taken daily over a longer run rather than as a one-off.
Contains shellfish-derived glucosamine unless the pack states otherwise — check before use if you have a shellfish allergy.
Good to know
- Format: caps
- Caffeine free
A food supplement, not a substitute for a varied diet and healthy lifestyle. Do not exceed the stated dose. Keep out of reach of children.
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