Doctor's Best Fully Active B12

Doctor's Best Fully Active B12

Brands: Doctor's Best
Regular price£10.65

If you want vitamin B12 without a cupboard full of separate bottles, this vcaps option from Doctor's Best is a sensible place to start.

Why people take it

  • Vitamin B12 contributes to normal red blood cell formation
  • Vitamin B12 contributes to the reduction of tiredness and fatigue
  • Vitamin B12 contributes to the normal function of the nervous system
  • Vitamin B12 contributes to normal energy-yielding metabolism

How to use

Take as directed on the pack, ideally with food and at the same time each day.

Good to know

  • Choose from 2 sizes: 180 vcaps / 60 vcaps
  • Format: vcaps
  • Caffeine free
  • Vegetarian-friendly capsule shell
Size: 60 vcaps
Quantity
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SKU: 753950002869

At a glance

£0.11

per daily dose

Strong

evidence for vitamin b12

Our honest take

Methylcobalamin B12 in vegetarian capsules, 1,500 µg each, sold in 60 and 180 counts. B12 is worth supplementing if you are vegan, older, or take metformin or acid-reducing medicines, and the larger tub brings the cost per capsule down a lot. The dose is far more than you need day to day, but B12 has no known upper limit and the body simply absorbs less of large doses. Methylcobalamin has not been shown to beat ordinary cyanocobalamin for most people.

  • You are vegan and want a reliable B12 source
  • You want a long-lasting tub: the 180-capsule size is the better value
  • You eat animal foods regularly and have no absorption problems
  • You have numbness, tingling or unexplained tiredness: see your GP for a blood test first
  • You have pernicious anaemia: you will usually need B12 injections from your GP
The science

Vitamin B12· evidence: Strong

Vitamin B12 is needed to make red blood cells and keep the nervous system working. It is found almost only in animal foods (meat, fish, eggs, dairy) and fortified foods, so vegans need a reliable source from fortified foods or a supplement. Older adults and people taking metformin or acid-reducing medicines absorb less B12 from food.

For these groups, B12 supplements are well proven to raise B12 levels and prevent deficiency. If you already eat animal foods and absorb B12 normally, extra B12 has not been shown to boost energy.

The body absorbs only a small share of a large oral dose, which is why many products use 500 to 1,000 µg. Methylcobalamin, cyanocobalamin and other forms all work; there is no good evidence that one form is better for most people. Pernicious anaemia and other absorption problems need a diagnosis and usually injections from your GP.

Authorised health claim
Vitamin B12 contributes to normal energy-yielding metabolism. Vitamin B12 contributes to normal functioning of the nervous system. Vitamin B12 contributes to normal homocysteine metabolism. Vitamin B12 contributes to normal psychological function. Vitamin B12 contributes to normal red blood cell formation. Vitamin B12 contributes to the normal function of the immune system. Vitamin B12 contributes to the reduction of tiredness and fatigue. Vitamin B12 has a role in the process of cell division. (Applies where a daily dose gives at least 15% of the NRV, i.e. 0.375 µg.)

Typical dose: Adults need about 1.5 µg a day (NRV on labels: 2.5 µg). Vegans: at least 10 µg a day or 2,000 µg a week (Vegan Society guidance). Supplements commonly give 10 to 1,000 µg.

Safety: No upper limit has been set because B12 has very low toxicity; the UK Expert Group on Vitamins and Minerals considered 2,000 µg a day from supplements unlikely to cause harm. Do not self-treat numbness, tingling, a sore tongue or unexplained tiredness: see your GP, as these can be signs of deficiency or pernicious anaemia that needs proper testing. Tell your doctor you take B12 before blood tests, as it raises your B12 result.

Research we looked at:
NHS. Vitamins and minerals: B vitamins and folic acid. nhs.uk/conditions/vitamins-and-minerals/vitamin-b
EFSA NDA Panel. Scientific opinion on dietary reference values for cobalamin (vitamin B12). EFSA Journal 2015;13(7):4150.
Expert Group on Vitamins and Minerals (2003). Safe Upper Levels for Vitamins and Minerals. Food Standards Agency.
NICE guideline NG239 (2024). Vitamin B12 deficiency in over 16s: diagnosis and management.

Ingredients & nutrition

Per daily dose (1 capsule): vitamin B12 (as methylcobalamin) 1,500 µg (60,000% NRV). 60 or 180 capsules, 60 or 180 daily doses.

Other ingredients: microcrystalline cellulose, hypromellose (vegetarian capsule). Suitable for vegetarians and vegans.

Always check the pack you receive, as manufacturers sometimes update recipes.

How to use

Take 1 capsule a day with a meal. Do not exceed the stated daily dose.

Price per dose & how it compares
ProductSizePricePer daily dose
This product60 vcaps£10.65£0.17
This product180 vcaps£21.43£0.11
Applied Nutrition Vitamin B12from £9.99£0.11
Osavi Liposomal Vitamin B12from £9.99£0.12
Cytoplan Vitamin B12from £12.41£0.21

Cost per daily dose lets you compare packs of different sizes fairly.Worked out from our current prices.

If you want vitamin B12 without a cupboard full of separate bottles, this vcaps option from Doctor's Best is a sensible place to start.

Why people take it

  • Vitamin B12 contributes to normal red blood cell formation
  • Vitamin B12 contributes to the reduction of tiredness and fatigue
  • Vitamin B12 contributes to the normal function of the nervous system
  • Vitamin B12 contributes to normal energy-yielding metabolism

How to use

Take as directed on the pack, ideally with food and at the same time each day.

Good to know

  • Choose from 2 sizes: 180 vcaps / 60 vcaps
  • Format: vcaps
  • Caffeine free
  • Vegetarian-friendly capsule shell

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