Size
Doctor's Best Chewable Fully Active B12
Vitamin B12 from Doctor's Best — 60 tablets per pack, no fuss.
Why people take it
- Vitamin B12 contributes to normal red blood cell formation
- Vitamin B12 contributes to the reduction of tiredness and fatigue
- Vitamin B12 contributes to the normal function of the nervous system
- Vitamin B12 contributes to normal energy-yielding metabolism
How to use
Take as directed on the pack, ideally with food and at the same time each day.
Good to know
- Format: tablets
- Caffeine free
A food supplement, not a substitute for a varied diet and healthy lifestyle. Do not exceed the stated dose. Keep out of reach of children.
At a glance
Strong
evidence for vitamin b12
Our honest take
A chewable B12 tablet using methylcobalamin, the form Doctor's Best calls "fully active". B12 is worth supplementing if you are vegan, older, or take metformin or acid-reducing medicines; chewables suit people who dislike swallowing pills. Methylcobalamin has not been shown to work better than standard cyanocobalamin for most people, so you are mostly paying for format. We could not verify the dose per tablet, so check the label.
- You are vegan and want an easy-to-take B12
- You find capsules hard to swallow and prefer a chewable
- You eat animal foods regularly and have no absorption problems
- You want the lowest cost: a plain B12 capsule is cheaper per day
- You have numbness, tingling or unexplained tiredness: see your GP for a blood test first
The science
Vitamin B12· evidence: Strong
Vitamin B12 is needed to make red blood cells and keep the nervous system working. It is found almost only in animal foods (meat, fish, eggs, dairy) and fortified foods, so vegans need a reliable source from fortified foods or a supplement. Older adults and people taking metformin or acid-reducing medicines absorb less B12 from food.
For these groups, B12 supplements are well proven to raise B12 levels and prevent deficiency. If you already eat animal foods and absorb B12 normally, extra B12 has not been shown to boost energy.
The body absorbs only a small share of a large oral dose, which is why many products use 500 to 1,000 µg. Methylcobalamin, cyanocobalamin and other forms all work; there is no good evidence that one form is better for most people. Pernicious anaemia and other absorption problems need a diagnosis and usually injections from your GP.
Vitamin B12 contributes to normal energy-yielding metabolism. Vitamin B12 contributes to normal functioning of the nervous system. Vitamin B12 contributes to normal homocysteine metabolism. Vitamin B12 contributes to normal psychological function. Vitamin B12 contributes to normal red blood cell formation. Vitamin B12 contributes to the normal function of the immune system. Vitamin B12 contributes to the reduction of tiredness and fatigue. Vitamin B12 has a role in the process of cell division. (Applies where a daily dose gives at least 15% of the NRV, i.e. 0.375 µg.)
Typical dose: Adults need about 1.5 µg a day (NRV on labels: 2.5 µg). Vegans: at least 10 µg a day or 2,000 µg a week (Vegan Society guidance). Supplements commonly give 10 to 1,000 µg.
Safety: No upper limit has been set because B12 has very low toxicity; the UK Expert Group on Vitamins and Minerals considered 2,000 µg a day from supplements unlikely to cause harm. Do not self-treat numbness, tingling, a sore tongue or unexplained tiredness: see your GP, as these can be signs of deficiency or pernicious anaemia that needs proper testing. Tell your doctor you take B12 before blood tests, as it raises your B12 result.
Research we looked at:
NHS. Vitamins and minerals: B vitamins and folic acid. nhs.uk/conditions/vitamins-and-minerals/vitamin-b
EFSA NDA Panel. Scientific opinion on dietary reference values for cobalamin (vitamin B12). EFSA Journal 2015;13(7):4150.
Expert Group on Vitamins and Minerals (2003). Safe Upper Levels for Vitamins and Minerals. Food Standards Agency.
NICE guideline NG239 (2024). Vitamin B12 deficiency in over 16s: diagnosis and management.
Ingredients & nutrition
Always check the pack you receive, as manufacturers sometimes update recipes.
How to use
Price per dose & how it compares
| Product | Size | Price | Per daily dose |
|---|---|---|---|
| Jarrow Formulas Methyl B-12 | from £10.28 | £0.10 | |
| Life Extension Vitamin B12 Methylcobalamin | from £11.35 | £0.11 | |
| Applied Nutrition Vitamin B12 | from £9.99 | £0.11 |
Cost per daily dose lets you compare packs of different sizes fairly.Worked out from our current prices.
Food supplements should not replace a varied, balanced diet and healthy lifestyle. General information, not medical advice. Speak to your GP or pharmacist first if you are pregnant or breastfeeding, have a medical condition or take medication.
Vitamin B12 from Doctor's Best — 60 tablets per pack, no fuss.
Why people take it
- Vitamin B12 contributes to normal red blood cell formation
- Vitamin B12 contributes to the reduction of tiredness and fatigue
- Vitamin B12 contributes to the normal function of the nervous system
- Vitamin B12 contributes to normal energy-yielding metabolism
How to use
Take as directed on the pack, ideally with food and at the same time each day.
Good to know
- Format: tablets
- Caffeine free
A food supplement, not a substitute for a varied diet and healthy lifestyle. Do not exceed the stated dose. Keep out of reach of children.
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