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Cytoplan 5-HTP Plus
Cytoplan 5-HTP Plus gives you 5-HTP in a straightforward vcaps format.
What it is
- Derived from Griffonia simplicifolia seed
How to use
Take as directed on the pack.
Good to know
- Format: vcaps
- Caffeine free
- Vegetarian-friendly capsule shell
A food supplement, not a substitute for a varied diet and healthy lifestyle. Do not exceed the stated dose. Keep out of reach of children.
At a glance
Insufficient
evidence for 5-htp (griffonia seed extract)
Our honest take
A capsule blend giving, per 2-capsule daily dose, 50 mg of 5-HTP from Griffonia seed, 20 mg of saffron extract, 100 mg of magnesium, 10 mg of vitamin B6 and 10 mg of zinc. Magnesium, B6 and zinc are useful at these amounts, but the 5-HTP and saffron have no authorised claims and the human studies are small, so we make no claims about mood or sleep. The important point is safety: it must not be combined with antidepressants or other serotonin-raising medicines, and it is not for use in pregnancy.
- You are a healthy adult on no regular medication who has decided to try 5-HTP
- You prefer a UK practitioner brand in a vegetarian capsule
- You take antidepressants, triptans, tramadol, St John's wort or L-tryptophan (risk of serotonin syndrome)
- You are pregnant, breastfeeding or under 18
- You have low mood, anxiety or ongoing sleep problems that your GP has not assessed
The science
5-HTP (Griffonia seed extract)· evidence: Insufficient
5-HTP (5-hydroxytryptophan) is made in the body from the amino acid tryptophan and is a step on the way to serotonin and melatonin. Supplements are extracted from the seeds of the African plant Griffonia simplicifolia.
The human studies on 5-HTP for mood, sleep and appetite are mostly old, small and of low quality. There are no authorised health claims, so we make no claims about what it does. If you have low mood, anxiety or ongoing sleep problems, please speak to your GP.
Typical dose: Products typically give 50 to 200 mg a day.
Safety: Do not take with antidepressants (SSRIs, SNRIs, MAOIs, tricyclics), triptans, tramadol, St John's wort, L-tryptophan or other serotonin-raising products: the combination can cause serotonin syndrome, which can be dangerous. Not for use in pregnancy or breastfeeding or by children. Can cause nausea. Speak to your GP or pharmacist first if you take any regular medication.
Research we looked at:
Turner EH, Loftis JM, Blackwell AD (2006). Serotonin a la carte: supplementation with the serotonin precursor 5-hydroxytryptophan. Pharmacology & Therapeutics 109(3):325-338.
Das YT, Bagchi M, Bagchi D, Preuss HG (2004). Safety of 5-hydroxy-L-tryptophan. Toxicology Letters 150(1):111-122.
Ingredients & nutrition
Always check the pack you receive, as manufacturers sometimes update recipes.
How to use
Food supplements should not replace a varied, balanced diet and healthy lifestyle. General information, not medical advice. Speak to your GP or pharmacist first if you are pregnant or breastfeeding, have a medical condition or take medication.
Cytoplan 5-HTP Plus gives you 5-HTP in a straightforward vcaps format.
What it is
- Derived from Griffonia simplicifolia seed
How to use
Take as directed on the pack.
Good to know
- Format: vcaps
- Caffeine free
- Vegetarian-friendly capsule shell
A food supplement, not a substitute for a varied diet and healthy lifestyle. Do not exceed the stated dose. Keep out of reach of children.
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